Challenge Challenge Challenge Challenge Challenge Challenge Challenge Challenge

Challenge

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Challenge

Questions from the floor There have been a lot of tough questions in the room. We’re going to gather your questions up and review them. Sandy will then give you a recap. We will take one outstanding idea per table. Questions: 1. Can patients truly give consent for an evolving system? 2. What is the plan to shorten the time getting results back to patients from 20 to 7 days? 3. How is the service transformation going to be funded and sustained? 4. What is the timeline to release key information to enable local planning? 5. Is NICE working with Genomics England? 6. How are NHS England an GEL going to support standardisation and optimisation of WGS reporting process? 7. What happens with staff post 30 September? Posters are gathered back from the teams and displayed on the windows again.

Sandy’s recap There’s a couple of questions about consenting, this is being reviewed to make it much shorter, to integrate it more into general practice so there isn’t a 3 hour conversation about consent. We’re trying to make it more efficient and appropriate. We will have the data scores which we can go back and reanalysis as our knowledge progresses. Times and results is a key issue, the best way is to get patient stories out there to make a difference to clinical management. The cancer fast track pathway is extending, we’re now down to 18 working days. Looking at how we can streamline the end to end pathway to make sure the results are coming back in a clinical actionable time. Please get in touch if you’re in a certain position - Ask. Funding - it’s fair to say GMC’s function will be required after September, the data isn’t going to disappear, they will continue in some form and guidance should be coming out in May with further information. We need to get the genomics thing out as a published public document. Is NICE working with genomics England - NICE is about clinical pathways and treatment, we’re working with many key stakeholders, not just NICE.

What do successful social movements do? • Define the change they want to see • Identify the pillars of power • Create a spectrum of allies • Seek to attract not overpower • Build a plan to survive victory Source: Satell G (2017) How to create transformational change, according to the world’s most successful social movements @NHSgmc @Genomics England #genomes 100 k

Action planning Tables: 1 - WM Alliance and Commissioning 2 - East Midlands GMC 6 - Other GMCs 8 - East of England GMC 10 - Sponsors 11 - National Teams were grouped together around their locality to work on their action plans.

Action planning

Action planning

Action planning

Action planning

Action planning

Action planning

Action planning

Popcorn feedback Helen will give the number of the table to give feedback first, and who’s next on the deck. When it’s your turn, pop up, say one thing you want to learn, and one thing you want to share (in one breath). And pop down again. @NHSgmc @Genomics England #genomes 100 k

Results from action planning Proud to share Want to learn Bringing together our somatic and inherited cancer scientific and clinical teams Interpretation of variants - standardisation, how to ensure it, infrastructure, workforce, political Regional network Future of GMS - structure, IT, finance Train and shadow between teams About FNAs to improve recruitment Progress made with analysing prelim results Examples of good practice from other GMCs Our expertise and experience to improve patient care Further development and implementation of project (post October) Biobank Recruiting biopsies for clinical trials Legacy samples How to improve TATs How far we’ve come so quickly How we can better connect to the right people in the wider cancer community

Our finale: “Snowstorm” and Volcano Write down on the white sheet one thing that has excited or inspired you most from today Write down on the flame coloured sheet one issue that we must take more account of On the signal throw your snowball and lavabomb in the air • Pick up one of each that lands near you • Snowball ‘and & and’ • Lavabomb ‘but & but Everyone picks up other people’s lava bomb and snowball and reflects if the comments resonate with their own thoughts.

Closing comments Dr Brian Thomson Director 100, 000 Genome Project Nottingham University Hospitals Director Nottingham Health Science Biobank Briefly, I want to say where we currently are. The first thing is there’s a strong sense of adventure. We’ve built on this exciting platform which is specifically personal. There has been a set of challenges which we’ve met and found that we’ve been redesigning the plane whilst we’ve been flying it. This is now a period of transition. It’s really important that we can understand manage this process of transformation. We need clarity on a large number of things such as biphomatic capacity do we need for these tests. With commonality, purpose and common challenges. @NHSgmc #genomes 100 k

Our team Facilitation team Helen Bevan Sasha Karakusevic Logistics team Zoe Lord Claire Randall Paul Woodley Camilla Lindo Report writer Rosie Redstone Lynnette Leman