Chromosome: • a coiled, double rodshaped form of condensed DNA that forms during cell division.
Reading anyone? ? ? • DNA is normally found in long strands in the cell nucleus. • The coiled structures we call chromosomes are found in cells only during cell division. • DNA is duplicated prior to cell division. When the chromosomes form, one side of each chromosome consists of the original cell DNA while the other side consists of the duplicated DNA. • One half of each chromosome goes to both cells during cell division. • This insures that the new cell will have exactly the same genetic make-up as the original cell.
Every species has a distinct number of chromosomes. • Humans have 46 chromosomes (23 pairs). Diploid Number (Body Cells) Haploid Number (Gametes) Human 46 23 Mouse 40 20 Garden Pea 14 7 Kangaroo 12 6 Domestic Fowl 36 18 Fruit Fly 8 4 Rye 14 7 Crayfish 200 100 Organism
Male Karyotype Female Karyotype
Since DNA condenses into them in cell division…you have to know what chromosomes are.
Why do cells divide? size and shape matter for function
SS – BIO – 10/20&21 Explain with detail your answer to the following question: Why do cells divide?
Why do cells divide? Some cells are big But this is not the norm….
• Watch this…
Binary Fission - Prokaryotes
Making a new Factory… • Must copy Blueprints. – What are the blueprints? • _ _ _ Replication • Rolled up Blue Prints = Chromosomes – Condensing
The Cell Cycle
Mr. W’s Rap Mitosis PMAT P– M– A– T– Pneumonic with gestures…
Plant Cell vs. Animal Cell
Draw an animal cell with 6 (2 n=6) chromosomes that is in anaphase. • Details! – Clearly label all components • Bonus: Will the daughter cells be haploid or a diploid cells?
Explore! …wanna see some reproduction?
Mitosis in Onion Root Tips
9. 3 – Cell Cycle Control
Cell Cycle Regulation
• Analogy – Washing machine dial
Cell Cycle Control in Eukaryotes • Cyclin - protein • Cyclin Dependent Kinase (CDK) – activates or inhibits production of needed proteins
Abnormal Cell Cycle… Cancer TEd Talk
Can you name others?
How can you reduce your risk of getting cancer? • Current Cancer Statistics. • US in 2015 “So your sayin’ there’s a chance…”
How can you reduce your risk of getting cancer?
Malignant vs. Benign tumors Metastasis
Carcinoma - Sarcoma Lymphoma - Leukemia - Myeloma
Parent CELL 2 Identical Daughter Cells
Review: Cellular Reproduction • Reason for division: Too big for central control & SA/Vol Ratio • Types: – Pro- Binary Fission – Eu- Mitosis • Mitosis = PMAT • Cell Cycle Regulation – Broken controls = cancer