Cell Therapy for Spinal Cord Injuries Shear Stress

  • Slides: 1
Download presentation
Cell Therapy for Spinal Cord Injuries: Shear Stress Commercial Manufacturing Facility A Class 4

Cell Therapy for Spinal Cord Injuries: Shear Stress Commercial Manufacturing Facility A Class 4 Study on the Feasibility of Industrial Scale Production Chris Redus Jessica Verbisky Hannah Pinard Department of Chemical Engineering Conclusions: • Plant produces 170, 946 doses/year (42, 750 treatments) • To achieve a internal rate of return of 50%, the price of a dose is set to be $905 • The plant lifetime is 15 years with a 1 year startup period Recommendations: Our team recommends continuing with the construction of this facility Breakdown of Manufacturing Expenses 1% 2% 3% Raw Materials 4% # of Neural Stem Cells Produced/ Year Breakdown of Fixed Capital 3. 42 x 1012 1% 1% Single Use Equipment 3% 4% Patents and Royalties # of Neural Cells/Dose 1% 0% Reactors 4% 20 x 106 15% Operating Labor & Supervisory and Clerical Labor Doses/ Year 170, 946 Operating Supplies & Laboratory Charges Overhead & Local Taxes & Insurance Price Per Dose $905 Revenue Per Year $155 M Separators • • • Mixers • Connie Sutton (Sartorius Group North America) Paul Todd (IKOTECH) Gale Ulrich and P. T. Vasu for creating Econ Expert Adam Steinberg (STERIS) Storage Vessels Maintenance and Repairs & Utilities 83% Acknowledgements: Pumps 78% Heat Exchangers Compressors References: Sharma, A. , Gokulchandran, N. , Sane, H. , Badhe, P. , Kulkarni, P. , Lohia, M. , . . . Thomas, N. (2013). Detailed Analysis of the Clinical Effects of Cell Therapy for Thoracolumbar Spinal Cord Injury: An Orginal Study. Journal of Neurorestoratology, 1(13), 22 nd ser. , 13 -22. Retrieved May 4, 2016.