Cell Membranes and Cell Signaling The Plasma Membrane

Cell Membranes and Cell Signaling

The Plasma Membrane Lay the phospholipid bilayer with the cytoskeleton facing toward you. Each color at the bottom represents a type of macromolecule. Can your group figure it out which types they represent?

The Plasma Membrane Add Cholesterol; Justify Choice

The Plasma Membrane Add protein passageways and docks. Which of the proteins are transmembrane proteins? Which of the proteins are channels? Which are “docks? ” Justify. . How are these three types of proteins different? What do all of these proteins have in common?

The Plasma Membrane Make a glycolipid and a glycoprotein. Justify.

Hydrophilic Signals • Hydrophilic signal is soluble in blood but can’t pass through the membrane of the target cell – Activates receptors from outside the cell – Generally active minutes to hours – Insulin and epinephrine for example 4 -21 -18 6

Hydrophobic signals • Fat soluble –travel in the blood attached to transport proteins – Can cross cell membranes to bind to intracellular receptors – Generally active days to weeks – Steroid hormones like estrogen, testosterone and cortisol 4 -21 -18 7

Modeling Intracellular Reception of Hydrophobic Molecules (like estrogen or testosterone) (Add the nucleus, Endocrine cell, and ribosome) Transport Protein Hormone Amino Acids Receptor RNA Ribosome Model with these pieces. Share. 4 -21 -18 DNA 8

References Raven, P. H. , and G. B. Johnson. (2002) Biology. 6 th ed. , Mc. Graw- Hill. Boston, MA Reece, J. B. , and N. A. Campbell. (2011) Campbell Biology / Jane B. Reece. Benjamin Cummings, Boston, MA