Cell Cycle Bits and Bobs Miss B NNHS

Cell Cycle Bits and Bobs Miss B NNHS biomissb@gmail. com biologymissb @biologymissb NNHSmissb. weebly. com

Boston College l l Private college located in Chestnut Hill 9000 undergraduates and 4500 graduate students Ranked as in top 35 by Forbes as best undergraduate schools in the US Lynch School of Education, Connell School of Nursing, BC Law School, Carroll School of Management 2014 -2015 Tuition & Fees $47, 436 Students 9, 049 enrolled 46% male / 54% female Admissions Jan. 1 application deadline 32. 2% accepted

Cell Cycle vs Cell Division l l l Cell Division is how unicellular organisms reproduce Cell division is one part of the cell cycle Multicellular organisms depend on the cell cycle to reproduce

How do Eukaryotic Cells Regulate Division l l l Cyclin-dependent kinases (Cdks) are regulatory proteins that work within the cell cycle. Part of the cell cycle control system Check points throughout cell cycle, (after G 1 and G 2) to ensure the cell is ready to divide

G 0 l l l Along with G 1 and G 2 there is another “gap/growth” phase known as G zero Resting phase within cell cycle Cell is not dividing nor is it preparing to divide

Why don’t Neurons Divide? l l l Cells such as heart muscle cells and neurons do not divide once they reach maturity These cells develop from stem cells, then will remain in G 0 or a “quiescent” state until they have served there time Then they will undergo apoptosis

Apoptosis l l l Programmed cell death or cell suicide Occurs when cell is no longer needed or becomes a threat to the organism (ie infection) Billions of cells in your intestines are dying each hour https: //www. youtube. com/watch? v=qjj. HKDn 12 q. I

Cancer Biology Miss B NNHS biomissb@gmail. com biologymissb @biologymissb NNHSmissb. weebly. com

What is Cancer? l l l Cell cycle is not regulated during cancer Cells excessively divide and invade other tissues Do not have Cdks

Benign Tumor l When abnormal cells remain at the original site.

Malignant Tumor l l l Cells whose genetic changes enable them to spread into new tissues Impair the functions of one or more organs An individual with a malignant tumor is said to have “cancer”

https: //www. youtube. com/watch? v=8 Lh. Qllh 46 y. I