CELL CYCLE AND CANCER Cell Division Mitosis During

CELL CYCLE AND CANCER

- Cell Division Mitosis • During mitosis, the cell’s nucleus divides into two new nuclei. One copy of the DNA is distributed into each of the two daughter cells.

Cell Division The -Cell Cycle

- Cell Division Length of the Cell Cycle How long does it take for a cell to go through one cell cycle? It all depends on the cell. A human liver cell, for example, completes one cell cycle in about 22 hours, as shown in the graph. Study the graph and then answer the following questions.

- Cell Division Length of the Cell Cycle • Reading Graphs: – What do the three curved arrows outside the circle represent? –The longest curved arrow represents the cell’s interphase; the shortest represents cytokinesis; and the middle one represents mitosis.

- Cell Division Length of the Cell Cycle • Reading Graphs: • In what stage of the cell cycle is the wedge representing growth? – Interphase

Length of the Cell Cycle • Interpreting Data: – In human liver cells, how long does it take DNA replication to occur? – 10 hours

- Cell Division Length of the Cell Cycle • Drawing Conclusions: – In human liver cells, what stage in the cell cycle takes the longest time? – Interphase

- Cell Division Structure of DNA • The DNA molecule is shaped like a twisted ladder. • How do the Nitrogen bases pair up? • Adenine – Thymine • Cytosine - Guanine

- Cell Division • What is it? Replication of DNA • When DNA make exact copy of itself • Do the nitrogen bases have to match up? • YES!! • How? • Adenine – Thymine • Cytosine - Guanine

Sequencing Can you name the stages and phases of Cell Cycle? Interphase Cytokinesis Cell grows, makes a copy of DNA. Mitosis: Prophase Chromosomes and spindle fibers form; nuclear envelope breaks down. Cell pinches in two; each daughter cell has same number of identical chromosomes. The Cell Cycle Chromosomes stretch out; new nuclear envelope forms around chromosomes. Mitosis: Telophase Mitosis: Anaphase Centromeres split; chromatids separate and move to opposite ends. Chromosomes line up across the center and attach to a spindle fiber. Mitosis: Metaphase

What Is Cancer? • Let’s find out • You will work in groups of 3 • Each group member will learn and then teach specific information about Cancer to the other team mates! • 1 st member will teach: WHAT IS CANCER • 2 nd member: TREATING CANCER • 3 rd member: CANCER PREVENTION • Each member will take notes • Finally everyone will have to answer 3 specific questions – we will review them!!

- Cancer What Is Cancer?