CD 4 positive Thelper cell responses to the

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CD 4 -positive T-helper cell responses to the PASD 1 protein in patients with

CD 4 -positive T-helper cell responses to the PASD 1 protein in patients with diffuse large B-cell lymphoma by Kamel Ait-Tahar, Amanda P. Liggins, Graham P. Collins, Andrew Campbell, Martin Barnardo, Maite Cabes, Charles H. Lawrie, Donald Moir, Chris Hatton, Alison H. Banham, and Karen Pulford haematol Volume 96(1): 78 -86 December 30, 2010 © 2011 by Ferrata Storti Foundation

Clinical details of the DLBCL cases studied. Kamel Ait-Tahar et al. Haematologica 2011; 96:

Clinical details of the DLBCL cases studied. Kamel Ait-Tahar et al. Haematologica 2011; 96: 78 -86 © 2011 by Ferrata Storti Foundation

Diagram to show the positions of the CD 4 PASD 1 peptides investigated here

Diagram to show the positions of the CD 4 PASD 1 peptides investigated here across the PASD 1 a and PASD 1 b protein isoforms. Kamel Ait-Tahar et al. Haematologica 2011; 96: 78 -86 © 2011 by Ferrata Storti Foundation

Summary of the CD 4 Th immune response to the PASD 1 peptides by

Summary of the CD 4 Th immune response to the PASD 1 peptides by DLBCL patients and normal donors. Kamel Ait-Tahar et al. Haematologica 2011; 96: 78 -86 © 2011 by Ferrata Storti Foundation

Comparison of the presence of a CD 4 Th response to PASD 1 in

Comparison of the presence of a CD 4 Th response to PASD 1 in DLBCL patients with clinical outcome. Kamel Ait-Tahar et al. Haematologica 2011; 96: 78 -86 © 2011 by Ferrata Storti Foundation

Interferon-γ ELISPOT studies showing CD 4 Th responses to PASD 1 peptides of patients

Interferon-γ ELISPOT studies showing CD 4 Th responses to PASD 1 peptides of patients 4 and 47. Kamel Ait-Tahar et al. Haematologica 2011; 96: 78 -86 © 2011 by Ferrata Storti Foundation

Cytolytic activity of PASD 1 -specific CD 4 Th cell lines derived from two

Cytolytic activity of PASD 1 -specific CD 4 Th cell lines derived from two DLBCL patients 4 and 47. Kamel Ait-Tahar et al. Haematologica 2011; 96: 78 -86 © 2011 by Ferrata Storti Foundation

Double immunofluorescent labeling of the cultured CD 4+ T-cell lines. Kamel Ait-Tahar et al.

Double immunofluorescent labeling of the cultured CD 4+ T-cell lines. Kamel Ait-Tahar et al. Haematologica 2011; 96: 78 -86 © 2011 by Ferrata Storti Foundation