CARDIOVASCULAR SYSTEM TRANSPORT O 2 CO 2 NUTRIENTS





















- Slides: 21
CARDIOVASCULAR SYSTEM TRANSPORT
• • O 2 CO 2 NUTRIENTS WASTE PRODUCTS & TOXINS HORMONES EXCESS HEAT PROTECTIVE CELLS/ SUBSTANCES
HEART – 2 PUMPS Body Lungs RV LV Lungs
EVENTS: RA Diastole RV RA Systole RV LA LV
INNERVATION OF HEART: PARASYMPATHETIC NERVE SUPPLY Right Vagus SA node Left Vagus RA AV node LA RV LV
Parasympathetic fibers: • • Dorsal motor nucleus of vagus Nucleus tractus solitarius Nucleus ambiguus Right vagus: Right atrium Sino-Atrial (S. A) node • Left vagus: Left atrium Atrio-Ventricular(A. V) node Bundle of HIS
VAGAL STIMULATION: • Chronotropic effect – Heart rate • Dromotropic effect – Rate of conduction • Bathmotropic effect – Excitability of heart • Inotropic effect – Myocardial contractility
SYMPATHETIC NERVE SUPPLY Superior Middle Inferior RA LA T 1 T 2 T 3 T 4 T 5 RV LV
Sympathetic fibers: • Upper thoracic segments (T 1 -T 5) • Right sympathetic fibers: Right atrium Right ventricle S. A. node • Left sympathetic fibers: Left atrium Left ventricle A. V. node
SYMPATHETIC STIMULATION: • Chronotropic effect – • Dromotropic effect – • Bathmotropic effect – • Inotropic effect – INNERVATION OF BLOOD VESSELS: Sympathetic fibers. Sympathetic cholinergic fibers. Parasympathetic fibers-
CARDIAC MUSCLE Intercalated disc Nucleus
SARCOMERE OF CARDIAC MUSCLE Cistern Sarcolemma T - tubule Actin filament L - tubule Myosin filament Sarcomere I - band A - band I - band Z- line
Source of Calcium L - tubule Ca++ T- tubule Ca ++ Cisterns
SARCOTUBULAR SYSTEM Cardiac muscle Skeletal muscle Organization: Level of T tubules: Diameter of T tubules: L tubules: Association of T & L tubules:
Contd- LEVEL OF T TUBULES Cardiac muscle Cisterns Z- line Myosin I-band A-band Skeletal muscle T-tubules Actin I-band A-band
Contd- TRIAD L-Tubules Ca ++ CARDIAC MUSCLE Cisterns T-tubules Ca ++ SKELETAL MUSCLE
DIFFERENCES BETWEEN MUSCLES: Smooth Fibres branched: Cross striations: Nucleus: Mitochondria: N-M junction: Sarcotubular system: Nerve supply: Cardiac Skeletal
Contd- Smooth Pacemaker tissue: Autorhythmicity: Refractory period: Action potential: Cardiac Skeletal
PACEMAKER & CONDUCTION TISSUES • Sinoatrial node – • Atrioventricular node – • Bundle of HIS – • Purkinje fibres -
SKELETON OF HEART • Fibrotendinous ring – Atria – Ventricle – • Impulse conduction – • Link between Atria & Ventricle – • Interventricular septum -
Valve ring Chordae tendineae Papillary muscle