Cancer Prevention and Early Detection Shaker A Mousa

Cancer Prevention and Early Detection Shaker A. Mousa, Ph. D, MBA, FACC, FACB The Pharmaceutical research Institute, Albany College of Pharmacy Albany, NY

Cancer Statistics Cancer is the #1 cause of death among working-age adults in the United States. • - One-third are caused by tobacco use. • - One-third are related to overweight/ obesity, physical inactivity, and nutrition. Preventable and curable cancers will continue to kill millions of people worldwide “Two-thirds of cancer deaths can be prevented” American Cancer Society --John Seffrin, CEO

Prevention and Early Detection • If people would just do four things: • -- engage in regular physical activity, eat a healthy diet, not smoke and avoid becoming obese – they could slash their risk of diabetes, heart attack, stroke or cancer by 80%, a new report has found. • Cancers that can be prevented or detected early by screening account for at least 50% of all new cancer cases. • Cancer Facts & Figures 2009

Preventable risk factors • Tobacco • Obesity • Physical inactivity • Alcohol • Sun exposure • Infections • Pollution

Tobacco • Tobacco kills more than 5 million people a year, an average of one person every six seconds. • It accounts for one in ten adult deaths worldwide. • Tobacco use, particularly smoking, is the single biggest cause of cancer in the world, responsible for more than a quarter of all cancer deaths, including cancers of the lung, mouth, throat, nose and sinuses, liver, pancreas, stomach, cervix, breast, bowel, kidney and bladder. • It also plays a in the development of a wide range of cardiovascular and pneumologic diseases. • Numerous studies have shown that stopping tobacco use and creating smoke free environments greatly reduces the risk of cancers and other short and long term health risks.

Maintain a Healthy Weight • - Balance caloric intake with physical activity • - Avoid excessive weight gain throughout life • - Achieve and maintain a healthy weight if currently overweight or obese

Adopt a Physically Active Lifestyle Adults: • Engage in at least 30 minutes of moderate to vigorous physical activity on five or more days a week (45 -60 minutes is preferable) Children: • Engage in at least 60 minutes per day on five or more days a week

Protect Yourself from the Sun • - Avoid direct exposure between 10 am and 4 pm when UV rays are the most intense • - Wear hats that shade the face, ears and neck and clothing that covers arms, legs • - Cover exposed skin with sunscreen of SPF 15 or higher • - Avoid tanning beds and sun lamps

Environmental carcinogens • Environmental pollution of air, water and soil with carcinogenic chemicals accounts for 1– 4% of all cancers (IARC/WHO, 2003). • Exposure to carcinogenic chemicals in the environment can occur through drinking water or pollution of indoor and ambient air. Exposure to carcinogens also occurs via the contamination of food by chemicals, such as aflatoxins or dioxins. • Indoor air pollution from coal fires doubles the risk of lung cancer, particularly among non-smoking women. Worldwide, indoor air pollution from domestic coal fires is responsible for approximately 1. 5% of all lung cancer deaths.

How to prevent cancer • Avoid tobacco • Eat healthy • Avoid alcohol • Exercise • Protect yourself from the sun • Vaccinate • Avoid pollution

Consume a Healthy Diet • - Watch portion sizes • - Eat 5 or more servings of fruit and vegetables each day • - Chose whole grains • - Limit consumption of processed and red meats • - No Alcohol Consumption

ﻥ ﺍ ﺍ ﻳﺍ ﺍ ﻳ ﺍ (36: 34)gardens ﺍﻭ . . and We establish of date-palms and vines [grow] thereon, and cause springs to gush forth within it • Dates and their chemical constituents have been shown to have anti-oxidant, cardioprotective, anti-cancer, as well as immunomodulating activities. • Grapes are rich in Polyphenols Mousa Shaker (USA), jouni Soad (KSA): Using Nano Co-encapsulation for the Prevention and Treatment of Various Disorders. US Patent 15, 011, 976; 02/2016

ﻭ ﺍﻟ ﺻﻠﻰ ﺍﻟﻠﻪ ﻋﻠﻴﻪ ﻭﺳﻠﻢ ﺍ ، ﺍﻟ ﻱ ﻳ - ﺍ ﻱ - ، ﻳ - ﺍ - ، ﺍ ﺍﻳ ، ﺍ ﻯ ﻯ ﺍ ﺍ ﺍﻵﺍ ، ﻯ ﻭ ، ﺍ ﻯ ﻯ ﻱ ﺍﺍ ﺍ ﺍ The 'ajwa' dates of 'Aliya' contain healing effects and these are antidote in the early morning Sahih Muslim . ﻱ ﺍ ﻻ ﺍ ﺍ ﺍ ﻭ ﺍﻟ ﺻﻠﻰ ﺍﻟﻠﻪ ﻋﻠﻴﻪ ﻭﺳﻠﻢ ، ﻳ ، ﺍ ﺍ ، ﺍﻟ "If somebody takes some `Ajwa dates every morning, he will not be affected by poison or magic on that day till night. " (Another narrator said seven dates). ﺍ Sahih al-Bukhari Mousa Shaker (USA), jouni Soad (KSA): Using Nano Co-encapsulation for the Prevention and Treatment of Various Disorders. US Patent 15, 011, 976; 2016

Effect of Dietary Antioxidants on Reactive Oxygen Species (ROS) N Engl. J Med 2014; 371: 177 -178.

Angiogenesis Supports Tumor Growth & Metastasis Vascularization Metastasis Micro-Environment - Inflammation - ROS - Pro-thrombotic State

Stay Healthy from Cancer. org http: //www. cancer. org/Healthy/index

Prophetic Medicine represents the Best Guidelines for Diseases Prevention