Cancer is genetic disease Cancer prone genetic disease

Cancer is genetic disease Cancer prone genetic disease Li-Fraumeni syndrome Von Hippel Lindau syndrome Cylindermatosis, Retinoblastoma FAP etc

http: //www. kbs. co. kr/1 tv/sisa/health/vod/1432657_941. html

Ch. 1 basis of cancer http: //www. cdc. gov/cancer/npcr/uscs/index. htm

Pancreatic cancer HCC

Breast colon

translocation inversion

+/- Ras -X -17 +/- Ras Dup(X? F 1? F 6) normal - 5 - 4 - 11 - 4 - 12 - 4 - 17 Del(12 B 3) 1 2 6 7 3 8 11 12 16 17 13 4 5 9 10 15 14 19 18 X +/- Myc - 8 +/- Myc 3 6 7 11 12 - 9 - 15 2 1 - 10 16 17 5 4 8 9 10 13 14 15 16 19 M cell line karyotype AIMP 3+/- Ras 80<4 n>, XX, -X, Del(3 F 1), +18 [3]/ 75 -82, idem, +Dup(X? F 1? A 6), +Der(X)T(XD; 17 D), -4, Del(12 B 3), +18, +mar [cp 12] AIMP 3+/- Myc 77 -84<4 n>, -1, -2, -3, -5, -6, -8, -9, +12, -13, -14, -15, -16, -17, 19, Del(4 A 5 or A 2 D 3)x 3 -4, Dic(4? A 5; 15 cen), Dic(4? A 5; ? 17 cen)Del(17 B 2), Dic(4? A 5; 10 A 4), Der(4)T(4? A 5; 12 A 2), Dic(4 C 4; 11 cen)Del(11 B 1), Der(5)T(5 E 2; 4 A 2)Dic(4 C 4; 11 cen)Del(11 B 1), Der(8)T(8 E; 10 C 1), Der (9)T(9 F 1; 15 D 3), +mar 1, +mar 2, +mar 3, +mar 4 [cp 14] X

reversible

www-medlib. med. utah. edu/Web. Path/webpath. html Hypertrophy of heart metaplasia normal Metaplasia: the exchange of normal epithelium for another type of epithelium. Metaplasia is reversible when the stimulus for it is taken away

Lipoma benign tumor

Metaplasia in esophagus Transition from squamous to column Dysplasia in colon

Dysplasia in skin Neoplasia / in situ cancinoma

adenoma adenocarcinoma

Benign vs malignancy Growth pattern: local vs invasion and meta Differentiation: well diff vs variable

sarcoma

anaplasia TNM system Size, lymph node, metastasis

Neoplasia in the pediatric age range is not common. Childhood malignancies are rare, but those that occur often have the appearance of primitive "small round blue cell tumors" such as the neuroblastoma seen here. These pediatric malignancies may include: Childhood Malignancy Location Leukemia / lymphoma Blood, marrow, lymph nodes Adrenal, extra. Neuroblastoma adrenal ganglia Medulloblasto ma Cerebellum Retinoblastom a Eye Wilms tumor Kidney Ewing sarcoma Bone