Building a Gene CODING STRAND Thymine Adenine Guanine

Building a Gene CODING STRAND Thymine Adenine Guanine Cytosine TIGERS ARE GREAT CATS A good way of remembering how the bases pair up. NONCODING STRAND 1. Draw on the first 10 bases of the coding strand. 2. Below write the genetic code for the coding strand e. g. it would start off as: TAT…………… 3. Now use the coding strand to build your protein chain. (You will have to use sheet 2 for this) 4. MUTATIONS!! A mutation in your DNA has changed the third cytosine of the non-coding strand into an adenine. How does this affect your protein? Another mutation has also caused the tenth base to be completely lost – how does this affect your protein?

The Genetic Code SHEET TWO Sets of three bases (codons) in the coding strand of the DNA are translated into amino acids in the course of protein synthesis according to the rules shown. The codons GTG and GAG, for example, are translated into pink and yellow. Each amino acid has a name but you will use coloured beads as the different amino acids. There are really more amino acids than shown here (there around 20 in humans). STOP codons show the end of a gene. 1 st position 3 rd position 2 nd position T C Yellow Green Red Blue T Yellow Green Red Blue C Yellow Green Red Blue A Yellow Green Red Blue G C Light Blue White Pink Red T Light Blue White Pink Red C Light Blue White Pink Red A Light Blue White Pink Red G A White Green Light Blue T White Green Light Blue C White Green Red Blue A Pink Green Red Green G STOP Blue Yellow Pink T STOP Blue Yellow Pink C Pink Yellow Pink A Pink Yellow Pink G T G A G