Blood Bag Coagulation Preservers Citrate 24 hours Heparin

Blood Bag

Coagulation & Preservers • • • Citrate 24 hours Heparin 48 hours ACD or CPD 21 days CPD-A 1 35 days CPD-A 1+ additive 42 days AS-1 • Additives AS-3 AS-5 1 -6 1 -6 1 -6 ºC ºC ºC

Additive Solution • Saline • Adenine • Glucose • Manitol

Blood Component

Blood Component • • • Whole Blood (WB) Packed Cell (PC) Washed Red Cell (WRC) Platelet Concentration Fresh Frozen Plasma (FFP) Cryo Precipitation Albumin Coagulation Factors Immunoglobulins

Whole Blood (WB) • • • ACD or CPD 21 days 1 -6 ºC CPD-A 1 35 days 1 -6 ºC CPD-A 1+ AS 42 days 1 -6 ºC Volume 450 cc ± 10% Usage = Sever Bleeding , Massive Transfusion , Surgery , Blood Exchange • Hct 40%

Packed Cell (PC) • • • ACD or CPD 21 days 1 -6 ºC CPD-A 1 35 days 1 -6 ºC CPD-A 1+ AS 42 days 1 -6 ºC Volume 220 - 260 cc Usage = Sever Bleeding , Anemia, Massive Transfusion , Surgery , Hemodialyze • Hct <80%

Washed Red Cell (WRC) • • Max 6 h in RT Max 24 h in 1 -6 ºC Volume 250 cc Usage = Reduces of fiver and allergic reactions with leukocytes and proteins. Prevention of anaphylactic shock.

Platelet Concentration • Count • Volume 5. 5 × 1010 50 - 70 cc • 3 – 5 days 20 – 24 ºC • Usage = Thrombocytopenia , Prevention of Bleeding , Cardiac-Pulmonary Bypass

Fresh Frozen Plasma (FFP) • 1 year -18 ºC • Volume 200 – 260 cc • Include = Proteins , Coagulation factors , Complement • Usage = Liver Disease , DIC , Coagulation factor deficiency , Massive Transfusion , Coagulation Disorders. • Do not use of FFP for increasing blood volume or nutrition.

Cryo Precipitation • VIII , VWF , XIII , Fibrinogen , Fibronectin • Volume 10 – 15 cc • 1 year -18 ºC • Usage = VWD , XIII and Fibrinogen Deficiency , Hemophilia A.

Albumin • • 3 years < 30 ºC 5 % 250 -500 cc 25 % 50 – 100 cc Usage = Hypovolumic Shock , Blood Proteins Deficiency , Cerebral Edema , Increasing Ancotic Pressure , Blood Pressure Control.