BIPAI Network Experience with multimonth prescribingrefills MMP All

BIPAI Network Experience with multi-month prescribing/refills (MMP) • All BIPAI sites provide MMP – Broad collective experience with implementation and monitoring of MMP • All sites start patients on monthly ART; move to MMP when patients are clinically stable and have good adherence The Baylor International Pediatric AIDS Initiative Experience with Multi-Month Prescribing of Anti-retroviral Medication. Wanless, S. 2016.

Standardized Pediatric Expedited Encounters for ART Drugs Initiative (SPEEDI)

SPEEDI Outcomes • January 2013 -December 2015: 1164 utilized SPEEDI • Good outcomes (active in care or transferred out): 98. 7% • Poor outcomes (died or LTFU): 1. 2% • Mortality of SPEEDI cohort: 0. 22 deaths/100 patient years (COE cohort prior to SPEEDI 2. 0 deaths/100 patient years) • Estimated 291 work hours saved through the program Bacha, J. Standardized Pediatric Expedited Encounters for ART Drugs Initiative (SPEEDI): Description and Evaluation of an Innovative Pediatric ART Health Service Delivery Model in Tanzania, 2016.

ART dosing. WHO adjustment intervals for children based on Weight-for-Age WHO median growth curves Growth Curves 35 Boys curve Girls curve Weight (kg) 30 25 -34. 9 kg 25 20 -24. 9 kg 20 14 -19. 9 kg 15 Weight-based ART dosing bands 10 -13. 9 kg 10 6 -9. 9 kg 5 3 -5. 9 kg 0 Approximate age when new ART dose is needed 0 2 6 12 18 24 2. 5 3 3. 5 4 4. 5 5 5. 5 6 6. 5 7 7. 5 8 8. 5 9 9. 5 10 3 months 15 months 3 years 6 years 8 years Age (in months for ≤ 24 months; in years for 2 -10 years) 4