BioNanotechnology Midterm Presentation Optodetection for The Microstructures of

報告格式 Bio-Nanotechnology Midterm Presentation

Opto-detection for The Microstructures of Tooth in Human for Caries Disease 姓名：詹小華 學號：R 93543099　 系級：應用力學所 碩一 Session: C 地點：應力所 306 室 日期： 2021/2/22 Bio-Nanotechnology Midterm Presentation

Title 32 points Ÿ Level 1 28 points - Level 2 24 points - Level 3 20 points Ÿ Use Arial or 標楷體 Ÿ The template is good for a seminar room with 10 rows of seats or less. If the room is bigger, use 28 points for level 1, 24 points for level, and 20 points for the rest. Ÿ ，。、；：！？「」『』（）【】＃� ＊※○◎□＋－ ×÷＜＞＝＄￥￡℃㎜㎝㎞㎏㏄ Bio-Nanotechnology Midterm Presentation

Color Template (1) 1 Color Bio-Nanotechnology H 6 S 81 L 189 H 14 S 100 L 183 H 35 S 255 L 227 H 67 S 32 L 180 H 121 S 255 L 54 H 129 S 255 L 74 H 130 S 255 L 83 H 135 S 110 L 211 H 143 S 71 L 176 H 144 S 193 L 218 H 147 S 255 L 57 H 149 S 255 L 70 R 210 G 174 B 168 R 211 G 173 B 154 R 255 G 246 B 199 R 178 G 189 B 170 R 0 G 108 B 93 R 0 G 143 B 147 R 0 G 157 B 165 R 192 G 224 B 230 R 154 G 182 B 198 R 190 G 225 B 246 R 0 G 63 B 113 R 0 G 70 B 139 H 151 S 118 L 125 H 152 S 163 L 58 H 165 S 83 L 205 H 167 S 108 L 66 H 201 S 119 L 58 H 238 S 255 L 69 H 240 S 134 L 158 H 253 S 167 L 151 H 0 S 0 L 221 H 0 S 0 L 255 R 67 G 120 B 182 R 21 G 53 B 95 R 188 G 192 B 221 R 38 G 42 B 94 R 71 G 31 B 85 R 137 G 0 B 55 R 209 G 107 B 144 R 219 G 83 B 90 R 221 G 221 B 221 R 255 G 255 B 255 Midterm Presentation

Hybridization experiment Three successive hybridization experiments with different 12 -mer oligonucleotide concentrations using one array. The concentra-tion detection limit was calculated to be 10 n. M. The buffer solution was manually J. Fritz et al. , Translating biomolecular recognition into nanomechanics, Science (2000), Vol. 288, pp. 316 -318. exchanged by a (16 or 18 points, Italian) micropipette. 若有用到別人的圖請在當頁加出處 Midterm Presentation Bio-Nanotechnology

Reference v http: //ccms. ntu. edu. tw/~juang/BCbasics/Nucleic 1. htm v G. Karp, Cell and molecular biology – concepts and experiments, John Wiley & Sons, 1999. v J. Fritz et al. , Translating biomolecular recognition into nanomechanics, Science (2000), Vol. 288, pp. 316 -318. v G. Wu et al. , Origin of nanomechanical cantilever motion generated from biomolecular interactions, PANS (2001), Vol. 98 (4), pp. 1560 -1564. v K. -M. Hansen et al. , Cantilever-based optical deflection assay for discrimination of DNA single-nucleotide mismatches, Analytical Chemistry (2001), Vol. 73, pp. 1567 -1571. v J. Thaysen et al. , Cantilever-based Bio-chemical sensor integrated in a microl-iquid handling system, IEEE (2001), pp. 401 -404. v R. Marie et al. , Adsorption kinetics and mechanical properties of thiol-modified DNA-oligos on gold investigated by microcantilever sensors, Ultramicroscopy (2002), Vol. 91, pp. 29 -36. Bio-Nanotechnology Midterm Presentation