Bellwork 215 Put your phone up Week 211
Bellwork: 2/15 Put your phone up Week 2/11 - 2/15 1. Describe the structure of DNA. 2. How do the nitrogenous bases pair? 3. What makes up a nucleotide?
1. 2. 3. 4. Today: Bellwork Finish Video Unit 5, Part 2 Notes Start DNA POGIL
Materials • Unit Book
This Week: • Monday: Bio. Tech Lab Prep • Tuesday: Bio. Tech Lab • Wednesday: Pt. 1 Notes & Video • Friday: Pt. 2 Notes
Homework • Quiz • Due Monday @11: 59 pm
Unit V: DNA & Molecular Genetics
Part 1 I: DNA Discovery & Replication
Discovery of DNA
Erwin Chargaff • 1950 s • Contribution: Discovered the 1: 1 ratio of base pairing (Chargaff’s Rule) • G=C • T=A
Rosalind Franklin • 1950 s • Contribution: Used xray diffraction on DNA molecules to discover its helical shape
Maurice Wilkins • 1950 s • Contribution: Deputy director of Franklin’s lab. Responsible for “taking” Franklin’s xrays & showing them to Watson & Crick
Watson & Crick • 1950 s • Contribution: Used Franklin’s x-rays to st develop the 1 doublehelix model of DNA
DNA Replication
Vocab Review!
Replication • Watson & Crick • Discovered DNA structure (kind of…not really…) • Revealed how replication works • Each DNA strand provides the information for complementary strand because of base pairing rules • A – T • G - C
When does DNA replication occur?
Where does DNA replication occur?
Cell Cycle
Replication • New DNA made by the enzyme DNA polymerase • During DNA replication, each strand of the original DNA is used as the template • DNA polymerase synthesizes the complementary new strand • DNA replication is considered semiconservative. WHY? • Keeps one original strand & makes one new strand
Activity! • Draw a diagram using two different colors of DNA replication for 3 rounds.
Think! • What would your diagram look like if it were conservative?
Bio Facts! • The human body has about 1 trillion cells that contain the 46 chromosomes in which DNA is stored. • If all of the DNA in one human cell were stretched end to end, it would form a line about 1. 8 M long. • The DNA that makes up a single human chromosome might be made up of more than 250 million nucleotides.
Answer Questions in Note Guide
- Slides: 23