BASKETLATE Basel Stent Costeffectiveness Trial Late Thrombotic Events

BASKET-LATE • Basel Stent Cost-effectiveness Trial –Late Thrombotic Events 药物支架成本-效果研究– 迟发性血栓事件研究

BASKET-LATE研究 • BASKET: 比� BMS与DES 6个月内的� 床效果 • BASKET-LATE: � 6个月内无事件� 生的患者停用� 吡格雷后，� 一步随� 12个月 n=746 PCI � 后6个月 无 事件者 使用DES者 n=502* n=826 PCI � 吡格雷＋ASA 停止使用� 吡格雷 n=244 使用BMS者 BASKET-LATE 6个月 12个月 *: � 物支架包括Cypher®和Taxus®支架两� Christoph Kaiser, et al. Lancet 2005; 366: 921– 29 J. Am. Coll. Cardiol. , 2006, 48(1), CS 7 -CS 8

CONCLUSION • Long-term efficacy of DES is persistent and the safety of DES is confirmed by meta-analysis based on patients level • Late stent thrombosis after DES implantation has emerged as a concerning entity Indication for DES stenting • Proper dual antiplatelet therapy, at least 1 year • For high risk patients or lesions, dual antiplatelet therapy may be longer than 1 year

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