Baseline BMI and AgeAdjusted Incidence of Diabetes Mellitus

Baseline BMI and Age-Adjusted Incidence of Diabetes Mellitus 35 White Men 30 25 Percent 30 35 20 15 White Women 25 20 15 10 10 5 5 0 0 <23 <26 <29 <32 <20 32 <23 35 32 35 Black Men 30 25 Black Women 25 Percent <32 Level of BMI 30 <29 <26 20 15 10 5 0 0 <23 <26 <29 <32 Level of BMI 32 <20 <23 <26 <29 Level of BMI NHANES I Epidemiologic Follow-up Study. 1971 -1987. Lipton R. B. et al. Am J Epidemiol 1993; 138: 826 -39. Bars: frequency distribution of body mass index (BMI). Squares and lines: incidence of diabetes (%). <32 32

Incidence of New Cases per 1, 000 Person-Years Obesity and Diabetes Risk BMI Levels Knowler WC et al. Am J Epidemiol 1981; 113: 144 -156.

Weight Gain and Diabetes Risk Relative Risk Weight Change Since Age 21 Body Mass Index at Age 21 Adapted from Chan JM et al. Diabetes Care 1994; 17: 960 -969.

Metabolic Characteristics of Non-Obese and Obese Women With Low and High Levels of Deep Abdominal Fat *Significantly different from non-obese women. +Significantly different from obese women with low levels of deep abdominal fat, p<0. 05. The values represent means + SD. The number of subjects is shown in parentheses. Triglyceride data were log 10 transformed for statistical analysis. Despres JP et al. Arteriosclerosis 1990; 10: 497 -511.

Incidence/1, 000 26 -Year Incidence of Coronary Heart Disease in Men BMI Levels Adapted from Hubert HB et al. Circulation 1983; 67: 968 -977. Metropolitan Relative Weight of 110 is a BMI of approximately 25.

Incidence/1, 000 26 -Year Incidence of Coronary Heart Disease in Women BMI Levels Adapted from Hubert HB et al. Circulation 1983; 67: 968 -977. Metropolitan Relative Weight of 110 is a BMI of approximately 25.

Relationship of BMI to Excess Mortality 300 Mortality Ratio 250 Age at Issue 20 -29 30 -39 200 150 100 Low Risk 50 0 15 20 25 30 Moderate High Risk 35 40 Body Mass Index (kg/[m 2]) Bray GA. Overweight is risking fate. Definition, classification, prevalence and risks. Ann NY Acad Sci 1987; 499: 14 -28.