AUSTRON Med AUSTRON RECFA Meeting Innsbruck March 26

AUSTRON / Med - AUSTRON RECFA – Meeting Innsbruck March 26, 2004 M. Regler

Early History • April 20, 1990: First presentation of a project frame at the RECFA Meeting at the Austrian Academy of Sciences by M. Regler (Co – author W. Mitaroff): Project for an international broad-field research and high-tech centre in Austria – AUSTRON • The final specification of the project – a Spallation Source, was taken in April 1991 at a Meeting of the “Working Group on Science and Technology” of the “Central European Initiative” (CEI, former Hexagonale, former Pentagonale) in Bratislava • October 1991: Workshop at CERN (hosted by C. Rubbia, organized by M. Regler): Quite detailed conceptual design report with a realistic cost estimate

Specifications • Rapid Cycling Synchrotron 1. 6 Ge. V / 25 Hz / 100 k. W with 4 k. J p/pulse on target; edge cooled target • Medical facility with protons and carbon ions • Total cost: 225 MEUR (prices 1991, without med. fac. ) • 1993/ 94: Feasibility Study (responsible: M. Regler, Accelerator group hosted at CERN with project leader Ph. Bryant (other members paid by Austria), project leader for target and experiments M. Schuster) • Ready December 1994: 200 k. W (by increased injection energy, 70 > 130 Me. V, Nr. of protons p/pulse: 3. 2*1013 • Separate Medical Facility similar to the EULIMA design

Continuation 1995 • Continuation with a very small team at CERN and in Austria (much weekend support by Austrian staff members at CERN): 0. 5 MW with a dual frequency magnet cycle (33/100 Hz); target still edge cooled (W 5 Re = Tungsten with 5% Rhenium) • Foundation of the AUSTRON Society (Regler/Skalicky (rector of the Univ. of Technology Vienna)) • Feasibility Study of a Medical stand - alone Facility financed by the City of Wiener Neustadt and the province of Lower Austria until 1999 • Joint effort Med-AUSTRON – TERA – CERN resulting in the encouraging PIMMS study (Austria: 3 Ph. D students) • Special Austrian contribution: Riesenradgantry

AUSTRON • 1996 Hearing by the European Science Foundation • 1997 recommendation to the Austrian Government to build AUSTRON after additional studies, mainly in the field of advanced and efficient instruments • 1998: As a parallel result of this additional studies: Storage Ring to deliver 500 k. W at 10 Hz > 2*1014 protons p/pulse (pulse length ~ 1 000 ns) • Peak neutron flux 4*1016/cm 2 s • 1999 – 2000: International contacts at the highest level, but • These activities were not really supported by the Austrian neutron scattering community! (“Dormant project”)

Med - AUSTRON • 2001 unanimous support by the Austrian Society of Radiooncology • 5 MEUR for “fotec” in Wiener Neustadt (director E. Griesmayer) for additional studies (25% medicine and biology, project leader Dr. Auberger (Innsbruck), 75% for accelerator studies (chief consultant A. Wrulich, supported by H. Schoenauer and many others), economic evaluation and PR) • Collaboration with the EU-ENLIGHT project, with CERN, “TERA”, GSI, Lyon, now also with SIEMENS • Waiting for Federal Government !!!

Weltweite Protonen- und Ionentherapiezentren Pionen 1. 100 Ionen 4. 290 Protonen 36. 111 TOTAL 41. 501 Stand Jänner 2004

Tiefendosisverhalten Energieabgabe Photonen Spread out Bragg Peak (SOBP) Querprofil Protonen Plateau Singel Bragg Peak (SBP) Eindringtiefe

Eindringverhalten in Gewebe Photonentherapie Protonen- und Ionentherapie.

low und high -LET 1 Me. V Protonen in H 2 O 1 Me. V/u C 6+-Ionen in H 2 O 0, 330 0, 325 0, 320 0, 315 symbolisch -5, 0 0, 0 5, 0 -3 x (µm) x 10 -0, 5 0, 0 5, 0 x (µm) x 10 -3

Aktives Scanning Tumor Dipolmagnete Letzte Schichte Erste Schichte Emin Emax

Standard-Technik Prot 2 Felder Prot 4 Felder Phot 4 Felder Prot 6 Felder

Diss. Stefan Reimoser RR-Gantry Banding Magnet ca. 120 t Patientenliege Strahlrichtung Behandlungsraum im Aufzug-Schienensystem Zugang für Personal/Patient

Layout Protonen - Energie - 60 - 250 Me. V/u 1 1010 - 120 - 400 Me. V/u 4 108 Teilchenzahl C-Ionen - Energie Teilchenzahl

Der Standort Wiener Neustadt