Astigmatism spherical aberration contrast vision and defocus of

Astigmatism, spherical aberration, contrast vision and defocus of 124 MICS cases in a multicentre study Jean-Claude Rigal-Sastourné The author of this poster has received travel expense reimbursement from Phys. IOL ASCRS 2010

Purpose n To evaluate the refractive outcomes in terms of astigmatism, spherical aberration, contrast vision and defocus, of microincision cataract surgery after implantation of a micro-incision aspheric intraocular lens. Methods n Prospective multicentre study n 124 eyes implanted with Micro AY (Phys. IOL) n n Four surgeons performing micro-incision cataract surgery: D. Deidier, G. Lesieur, P. Rozot, JC Rigal-Sastourné Examinations at 1 week (124 eyes) and 3 month (101 eyes) ASCRS 2010

IOL Features Micro AY lens (Phys. IOL) n 25% hydrophilic acrylic n 10. 75 mm overall diameter n 6. 15 mm aspheric optic n Blue blocker n 360° square edge n 5° angulation Micro. Set injection system n 1. 8 to 2. 2 mm incisions ASCRS 2010

Population n Mean age 73. 5 ± 8. 3 (range 51 -89) 54% female, 46% male Cataract type: 50. 8% nuclear, 20. 2% cortical, 16. 9% subcapsular Surgery n n Topical anaesthesia: 96% Clear corneal incision: 100% Bi-axial technique (1 to 1. 3 mm incision): 74. 2% Co-axial technique (2. 2 mm incision): 25. 8% ASCRS 2010

Results Mean incision size Phaco IOL* All surgeries (n = 124) 1. 41 1. 95 Bi-axial group (n = 92) 1. 14 1. 79 Co-axial group (n = 32) 2. 2 2. 4** * Mean IOL power: 20. 82 D (min 12, max 28) ** Unenlarged in all cases but 4 for astigmatism reduction Endothelial cells Preop Postop Loss All surgeries (n=84) 2369 cell/mm 2 2222 cell/mm 2 6. 2% Bi-axial group (n=63) 2338 cell/mm 2 2196 cell/mm 2 6. 1% Co-axial group (n=21) 2462 cell/mm 2 2300 cell/mm 2 6. 6% ASCRS 2010

Results Visual acuity Pre-op (n=124) UCVA 0. 21 ± 0. 15 BCVA 0. 48 ± 0. 18 Post-op 3 month (n=101) 0. 72 ± 0. 22 0. 97 ± 0. 08 Potential post-op BCVA of less than 0. 6 were excluded from the study Refraction Pre-op (n=124) Post-op 3 month (n=101) Spherical equivalent Cylinder -0. 51 ± 2. 31 -0. 34 ± 0. 87 -0. 36 0. 78 -0. 14 ± 0. 71 Cylinder less or equal to preop in 72. 3% of cases ASCRS 2010

Results Spherical aberration Mean Z 4. 0 (n=15) Range Corneal preop Micro AY IOL Total post-op +0. 24 ± 0. 13 -0. 11µ 0. 10µ ± 0. 11 -0. 09 to +0. 31 -0. 12 to +0. 24 Contrast vision 100% contrast 25% contrast 9% contrast log. MAR VA (n=28) -0. 08 0. 07 0. 11 0. 14 e-type ASCRS 2010

Results Defocus curve (n=28) ESCRS 2009

Results Comparison of defocus curve 1. 0 0. 79 0. 95 0. 76 0. 72 0. 53 0. 33 0. 50 0. 45 0. 4 0. 35 0. 28 ESCRS 2009

Conclusion Good visual outcomes with low levels of astigmatism, good visual acuity and good contrast vision were observed in this study three months after MICS and implantation of an aspheric micro-incision lens. When aberrometry was performed, most eyes ended with an expected slightly positive balance of spherical aberration. Defocus curves have shown only a slight decrease of depth of focus in comparison to spherical IOLs. No complications were due to the implant: there were no problems during insertion, no IOL deposits and no posterior capsule early opacity. ASCRS 2010