Animal Biotechnology Dr Ahmad Ali Shahid Lecture 6
Animal Biotechnology Dr Ahmad Ali Shahid Lecture - 6
Animal Biotech • Animals provide a number of products we use in every day life. • Milk • Leather • Wool
Animal Biotech • Eggs • Meat
Roles of Animals in Biotech • Animals are involved in lab experiments. • Without the use of animals humans might be in danger.
Animal Models • 4 models apply for the use of animals. • Living animals • Living animal tissues or systems • Non-Living systems
Animal Models • Computer and Mathematical approaches
Living Animals • These animals are living and usually have no threat to their well being. • Such animals may be known as laboratory or scientific animals.
Living Animals • Agricultural Research often uses experimental groups of animals.
Living animal tissues or systems • Animal tissues can be cultured in a lab. • This saves the use of animals as well as the expense of feeding, housing, and cleaning up after the animals.
Non-Living Systems • Involves using non living mechanical models that reflect animal activity. • These often relate to skeletal movement and locomotion
Non-Living Systems • Artificial replacement parts, such as hip joints can be studied using non living systems.
Computer and mathematical approaches • Computer simulations with virtual reality and other uses help in biotechnology. • Computer modeling may be done with a propose biotechnology practice before it is tested with animals.
Laboratory animals • A laboratory animal is an animal used for laboratory or research purpose. • Good tending is needed to assume that the research is properly carried out.
Laboratory animals • Without research involving animals, scientists would not have a base.
Animal Species • Most animals are subjects of study at one time or another. • Most common species used in research laboratories are mice, rats, and hamsters.
Animal Species • A primate is an animal with thumb and forefinger opposition. • A non human primate is similar to humans but is not a human.
Animal Reproduction • Reproduction is a process by which offspring are produced. • Sexual Reproduction is the union of a sperm and egg to ultimately produce a new individual.
Artificial Insemination • Artificial insemination is the transfer of collected semen to a recipient female. It is used with sheep, beef cattle, turkeys, and swine. • Generally female estrous cycles are regulated with hormone injections.
Embryo Transfer • Embryo transfer is the harvesting of fertilized ova from a donor and implanting them into a recipient. • The harvested embyros are transferred to a recipient.
Embryo Transfer • Non surgical transfer involves flushing the embryos from the uterine horn.
Bovine Somatotropin • Bovine somatotropin is a natural occurring growth hormone produced in the pituitary gland in the endocrine system. • By treating dairy cattle with the hormone, milk production is increased approximately 15%.
Bovine Somatotropin • Some small dairy producers do not use BST and incorporate that fact in their advertising.
Transgenic Animals and Products • Pigs- have been used to manufacture human hemoglobin. • A xenograft is the practice of grafting an organ or a tissue from one species into another.
Transgenic Animals and Products • Mice- transgenetic mice have been used in several ways. one of the best known is to produce human antibodies. • Cattle- are used to control disease such as mastitis in dairy cows.
Methods of creating transgenetic animals • Step One- collect embryos • With proper stimulation far more embryos can be obtained than would be the natural result of the reproductive process.
Methods of creating transgenetic animals • Step Two- Inject embyros. • A pro nucleus is the haploid nucleus of the sperm or ovum that have united in fertilization to form a zygote.
Methods of creating transgenetic animals • Step Three- Zygote Culture • The zygotes are placed in the oviduct of a recipient female.
Thank You
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