An Effective Approach to a Proven Therapy Why

An Effective Approach to a Proven Therapy

Why the BAERVELDT® Glaucoma Implant? • Unique design combines a large surface area implanted in a single quadrant. More surface area provides: – More effective long-term IOP control 1, 2 – Increased drainage capacity 2 – Potentially fewer postoperative anti-glaucoma medications 1, 2

Single-quadrant BAERVELDT® Glaucoma Implant May Provide: • • Easier implantation 1 Less trauma to periocular tissue than multiple quadrants 2 Minimal inflammation 2 Improved control of IOP as a result of minimizing inflammation 2

Single Implant Surface Area (mm 2) 1 1 3 4

The Advantages of the BAERVELDT® Glaucoma Implant • Single-quadrant insertion 1 • Technically easier surgery, requiring only one conjunctival incision compared to 2 -quadrant implants 1, 2 – Reduced surgical time 2 – Less trauma to periocular tissue 2

The Advantages of the BAERVELDT® Glaucoma Implant • Patented bleb control mechanism – Fenestrations allow fibrotic tissue growth, ‘riveting’ bleb to sclera 1, 5, 6 – Designed to control bleb height and volume 1, 6 – Secures the plate in place 6 – Minimizes potential for ocular motility disturbances 6

The Glaucoma Implant – Designed for Ideal Pars Plana Implantation • Exclusive Hofmann Elbow directs the drainage tube for proper placement in the posterior chamber and eliminates the need for trimming or modification.

BAERVELDT® Pars Plana Glaucoma Implant – Designed for Clinical Success • Excellent IOP control 1 • Visual acuity remained the same or improved in 83% of patients (10 out of 12)7 • No reported cases of vitreous incarceration Reference 8

An Implant Designed from the Surgeon’s Perspective • Unique design with Hofmann Elbow facilitates proper placement in the posterior chamber • Eliminates the need to trim or modify the drainage tube for insertion through the pars plana • Eliminates concerns over potential straightening of the tube

The BAERVELDT® Glaucoma Implants – Effective Implant Designs • Large surface area for effective IOP control 1 • Low implant profile helps reduce complications 1 • Single-quadrant insertion for installation with less trauma than double plate • Fenestrations minimize bleb height and volume to reduce ocular motility disturbances 1, 5, 6

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

BAERVELDT® Glaucoma Implant Surgical Technique

References 1. 2. 3. 4. 5. 6. 7. 8. Lloyd MA, Baerveldt G, Fellenbaum PS, et al. Intermediate-term results of a randomized clinical trial of the 350 - versus the 500 mm 2 Baerveldt Implant. Ophthalmology. 1994; 101: 1456 -64. Fellenbaum PS, Sidoti P, Heuer DK, et al. Experience with the Baerveldt implant in young patients with complicated glaucomas. J Glaucoma. 1995; 4: 91 -7. Heuer DK, Lloyd MA, Abrams, DA, et al. Which is better? One or two? A randomized clinical trial of single-plate versus double-plate Molteno implantation for glaucomas in aphakia and pseudophakia. Ophthalmology. 1992; 99: 1512 -19. www. ahmedvalve. com/products/silicone/fp 7. html. Accessed March 6, 2006. Data on file, Advanced Medical Optics, Inc. Hodkin MJ, Goldblatt WS, Burgoyne CF, et al. Early clinical experience with the Baerveldt implant in complicated glaucomas. Am J Ophthalmol. 1995; 120: 32. BAERVELDT glaucoma implant package insert, Advanced Medical Optics. Luttrull JK, Avery RL. Pars plana implant and vitrectomy for treatment of neovascular glaucoma. Retina. 1995; 15: 379 -87. BAERVELDT is a registered trademark of Advanced Medical Optics, Inc.