Addisonian crisis Fares alshaer Addisonian crisis also known

Addisonian crisis Fares alshaer

• Addisonian crisis : • (also known as Adrenal crisis and acute adrenal insufficiency) is a medical emergency and potentially life-threatening situation requiring immediate emergency treatment. • It is a number of symptoms that indicate severe adrenal insufficiency caused by insufficient levels of the hormone cortisol. • This may be the result of either previously undiagnosed or untreated Addison's disease.

• • • Adrenal crisis is caused by a deficiency of cortisol resulting from: Addison's disease congenital adrenal hyperplasia (CAH) Infection (TB, sarciodosis ) pituitary disorders (such as Sheehan's syndrome, pituitary adenoma, hypopituitarism ) causing failure to activate the adrenal glands. • Rapid cortison stop

Signs and symptoms • Sudden penetrating pain in the legs, lower back or abdomen • Confusion, psychosis, slurred speech • Severe lethargy • Convulsions • Fever • Hypotension (low blood pressure) • Severe vomiting and diarrhea, resulting in dehydration • Syncope (loss of consciousness and ability to stand)

• Hyperkalemia (elevated potassium level in the blood) • Hypercalcemia (elevated calcium level in the blood • Hypoglycemia (reduced level of blood glucose) • Hyponatremia (low sodium level in the blood) • Hypotension (low blood pressure) • Hypothyroid (low T 4 level)

Diagnosis • ACTH (cosyntropin) stimulation test • Cortisol level (to assess the level of glucocorticoids) • Fasting blood sugar • Serum potassium (to assess the level of mineralocorticoids) • Serum sodium

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