Acute Kidney Injury Treatment with Unani MedicineCase Report
- Slides: 12
Acute Kidney Injury: Treatment with Unani Medicine—Case Report Muhammad Shakil Ahmad Siddiqui* , Khan Usmanghani Rafah-e-Aam Dawakhana Ajmali (Clinics) and Rafah-e-Aam Herbal Laboratories, Karachi, Pakistan
Definition of AKI Ø Impairment of kidneys functions over a period of hours and days. Ø Results in retention of toxins, fluids and end products of metabolism Ø A diagnose of AKI is made on the basis of presence of elevated serum creatinine and/or blood urea nitrogen (BUN) levels and/or decreased urine out put. Ø Sudden reduction in kidney function and are associated with morbidity and mortality. Ø May progress to Chronic Renal failure or End Stage Renal Disease(ESRD).
Acute Kidney Injury: Treatment with Unani Medicine—Case Report Causes Ø PRERENAL Ø Hypovolemia, shock, blood loss, embolism, ascites or burns, cardiovascular disorders, sepsis Ø RENAL Ø Nephrotoxic agents, infections, ischemia and blockages, polycystic kidney disease Ø Postrenal Ø Stones, blood clots, BPH, urethral edema from invasive procedures
Increase in SCr Urine output Risk of renal injury 0. 3 mg/dl increase < 0. 5 ml/kg/hr for > 6 h Injury to the kidney 2 X baseline < 0. 5 ml/kg/hr for >12 h Failure of kidney function 3 X baseline OR > 0. 5 mg/dl increase if Anuria for >12 h SCr >=4 mg/dl Loss of kidney function End-stage disease Persistent renal failure for > 4 weeks Persistent renal failure for > 3 months Am J Kidney Dis. 2005 Dec; 46(6): 1038 -48 RIFLE criteria for diagnosis of AKI based on The “Acute Dialysis Quality Initiative”
Acute Renal Failure Diagnostic tests BUN, Serum creatinine, Serum Electrolytes Hgb and Hct Urine D/R Urine C/S US of kidneys KUB Retrograde pyloegram Renal CT/MRI
Research Presentation _Abstract A male named Anwer Jamal, age 45 years, married, visited Clinic Rafaheaam Dawakhana Ajmali on March 29, 2013, with history of glomerulonephritis, inherited renal diseases, hypertension and previously hooked on voltaren 50 (Diclofenic Sodium, 50 mg) and was not on dialysis. Different diagnostic parameters showed the patient was suffering from acute renal failure according to the RIFLE criteria. The patient was treated and managed with herbal medicines according to Unani system of medicine. Reversal of the parameter such as serum creatinine from 7. 90 mg/dl (6. 58 fold high) to 0. 81 mg/dl within two weeks clearly shows the remarkable recovery in a short period of time. During this period the other related parameters e. g. blood urea nitrogen (BUN), serum albumin, albuminuria, blood pressure were also normalized whereas clinical sign and symptom exhibited improvement. .
Pateient Kidney Function Test
Unani (Herbal) Medicine Ø Majun Mussafi Khas Chob Chini (Smilax chinensi Linn), Senna Makki (Cassia senna Linn), Turbud (Ipomea turpenthum R. Br. ), Nigand Babri (Vitex negundo Linn). Ø Qurs Rasoot: Rasoot (Berberis aristata D. C. ) Haleela Zard (Terminalia chebula Retz half ripe fruit) Ø Qurs Podina: Zinjabeel (Zingiber officinale Rosc), Kala Zeera (Carum carvi Linn), Podina (Mentha piperita Linn), Ajwain (Trachyspermum ammi (L. ) Sprague), Filfil Daraz (Piper longum Linn) at noon after lunch; Ø Habb e Sibr (Aloe vera L. Burm f. ) or constipation, Ø Itrifal Kishnizi: Haleela Zard (Terminalia chebula Retz) , and Haleela Siyah (Terminelia chebula Retz. uripe fruit) and Kashneez (Coriandrum sativum Linn) , Ø Hab-e-Fishar (Rauwolfia serpentina (L. ) Benth ex Kurz) for blood pressure) at night after meal.
Unani Medicine priscription 2 &3 Ø Majun Mussafi Khas Chob Chini (Smilax chinensi Linn), Senna Makki (Cassia senna Linn), Turbud (Ipomea turpenthum R. Br. ), Nigand Babri (Vitex negundo Linn). Ø Sherbet Bazoori: Kasni (Cichorium intybus Linn), Kharpazza (Cucumis melo Linn), Badyan (Foeniculum vulgare Mill) Ø Sodium bicarbonate Tablet after meal; Ø Itrifal Kishnizi: Haleela Zard (Terminalia chebula Retz) 0. 43 mg, and Haleela Siyah (Terminelia chebula Retz. uripe fruit) 0. 21 mg and Kashneez (Coriandrum sativum Linn) 0. 21 mg. Ø Unani Prescription 3. Jawarish Zarooni Saida
Follow up Ø On 08 May, 2013, serum creatinine 0. 87 mg/dl. urine specific gravity 1020, p. H 6. 0, Protein, Blood, Pus cells, Cast, Bacteria was reported NIL Blood pressure was 120/80 mm∙Hg, no lumber pain, no edema, urine output was normal. Ø On June 12, 2013, the serum creatinine 0. 76 mg/dl. urine D/R specific gravity 1. 030, p. H 6. 0, Urine albumin negative, blood nil, pus cell 4 - 6/HPF, RBC, casts, crystals were nil, bacteria reported few and 24 hrs. creatinine clearance(Cr. Cl. ) was 64. 4 ml/min. (60 - 170 mg d. L).
Conclusion Ø Unani herbal preparations have resolved acute kidney injury within 20 days. BUN, serum creatinine and 24 hour serum creatinine clearance levels become in normal ranges. Ø After 35 days showed sustained improvement. Monitoring for another 15 days showed sustained improvement. Serum creatinine does not rise to abnormal levels until a large proportion of the renal mass is damaged, because the relationship between the glomerular filtration rate (GFR) and the serum creatinine level is not linear, especially early in disease. Ø The data presented clearly represent where in creatinine level on March 29, 2013 at 7. 90 mg d. L and on April 15, 2013 it decrease to 0. 81 mg d. L.
Thank you!
- Acute kidney injury
- Unani meaning
- Sistem medis kosmopolitan
- Battering intentional or unintentional
- Acute abdomen treatment
- Is gout like arthritis
- Acute abdomen treatment
- Acute pancreatitis pathophysiology
- Acute cholecystitis treatment
- Subsequent report of injury
- Project progress status
- Partial report technique
- 7 functions of the kidney