A Short Journey with Radicals Dr Chandrakanta Bandyopadhyay

A Short Journey with Radicals Dr. Chandrakanta Bandyopadhyay Department of Chemistry Ramakrishna Mission Vivekananda Centenary College Rahara Kolkata-700118

A Short Journey with Radicals It is always a pleasure to organic chemists to make a journey with radicals because of the following reasons: Ø It has dual character (electrophilic and nucleophlic radicals), which is not at all problematic but highly accommodative. Ø It is soft in nature. Ø It often makes fun by exhibiting its opposite behaviour (umpolung) compared to the conventional one (nucleophilic and electrophilic character). Ø High selectivity during halogenation of alkanes.

TS 2 8 kcal TS 4 TS 1 8. 5 kcal 1 kcal TS 3 12. 5 kcal P. E 8. 5 kcal R. C. of Chlorination R. C. of Bromination

REFERENCES A Guide Book to Mechanism in Organic Chemistry: P. Sykes Physical Organic Chemistry: N. S. Issacs Organic Chemistry: J. Clayden, N. Greeves, S. Warren and P. Wothers Frontier Orbitals organic Chemical Reactions: I. Fleming Radicals in Organic Chemistry: B. Giese

ACKNOWLEDGEMENT Swami Shukadevananda Principal Ramakrishna Mission Vivekananda Centenary College Rahara, Kolkata – 700 118 All my departmental colleagues in Ramakrishna Mission Vivekananda Centenary College Rahara, Kolkata – 700 118