A Model of Chronic Temporal Lobe Epilepsy Presenting

A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology Upadhya Dinesh, Kodali Maheedhar, Gitai Daniel, Castro Olagide W, Zanirati Gabriele, Upadhya Raghavendra, Attaluri Sahithi, Mitra Eeshika, Shuai Bing, Hattiangady Bharathi, Shetty Ashok K Institute for Regenerative Medicine, Department of Molecular and Cellular Medicine, Texas A&#x 00026; M Health Science Center College of Medicine, College Station, TX, USA Figure 4. Comparison of daily EEG data from daylight (6 AM to 6 PM) and night (6 PM to 6 AM) periods in the 5 th and 6 th month after status epilepticus (SE). The bar charts in A 1 and A 3 illustrate consistently higher frequencies of SRS (A 1) and Stage-V SRS (A 3) in daylight periods than night periods in the 5 th month after SE. The bar charts in A 2 and A 4 compare the average frequency of SRS (A 2) and Stage-V SRS (A 4) over 21 consecutive Aging and Disease, 2019, 10(5), 915 -936. DOI: 10. 14336/AD. 2019. 0720 days between the daylight and night periods in the 5 th month after SE. The bar charts in B 1 and B 3 illustrate higher frequencies of SRS (B 1) and Stage-V SRS (B 3) in daylight periods than night periods in the 6 th month after SE. The bar charts in B 2 and B 4 compare the average frequency of SRS (B 2) and Stage-V SRS (B 4) between the daylight and night periods in the 6 th month after SE. &#x 0002 A; , p&#x 0003 C; 0. 05; &#x 0002 A; , p&#x 0003 C; 0. 01; &#x 0002 A; , p&#x 0003 C; 0. 001; NS, not significant.