A karyotype DAS client DAS workshop 2009 10

A karyotype DAS client DAS workshop 2009 10 th March Rafael Jimenez

Introduction Visualization of genome data in combination with experimental data and genome analysis helps to formulate testable hypothesis. Eukaryotic Genome browsers specialized to represent annotations on. . . Specific chromosomes Genome regions in one chromosome Detailed views on genome regions Eukaryotic genome analysis requires visualization in a higher representation level. . . Full genomic context -> Karyotype

Karyotype DAS client DAS web browser to visualize Eukaryotic genome data at the level of karyotype, chromosome and cytoband. Still a prototype! For more detail views in a lower representation level it interacts with the Ensembl web browser. Karyotype DAS viewer Karyotype Chromosome Ensembl Genome region Detailed view

Implementation Service Oriented Architecture Service broker Publish Find Service consumer Service Contract. . . Interact Service provider

Implementation Distributed Annotation System DAS Registry Gene Expression Profile Analysis Suite GPAS Publish Find Provide DAS. . Karyotype DAS Client Interact Ensembl Genome Analysis Sources Cromosome Type

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1 Quantitative (score) Genome region +/sources by view Chromosome Karyotype Qualitative

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binning: maxbins 3. 1

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Thank you! Thanks for its support to … Bioinfomatics department … especially for his contribution on this project to … Joaquin Tarraga Thanks to our collaborators … UCT South Africa CBIO, UCT South Africa