8 3 DNA Replication KEY CONCEPT DNA replication

8. 3 DNA Replication KEY CONCEPT DNA replication copies the genetic information of a cell.

8. 3 DNA Replication Warm up! • What makes the new DNA strand complementary to the original strand?

8. 3 DNA Replication Vocabulary tip • Complement: either of two parts that completes a whole. • Compliment: expresión of praise.

8. 3 DNA Replication copies the genetic information. • A single strand of DNA serves as a template for a new strand. • The rules of base pairing direct replication. • DNA is replicated during the S (synthesis) stage of the cell cycle. • Each body cell gets a complete set of identical DNA.

8. 3 DNA Replication Enzymes • Helicase: unzip the DNA and separate the nucleotides of the two strands • DNA polymerase: (meaning on the book) • Ligase: bond together the nucleotides after the replication

8. 3 DNA Replication Proteins carry out the process of replication. • DNA serves only as a template. • Enzymes and other proteins do the actual work of replication. – Helicase unwind and unzip the double helix.

8. 3 DNA Replication Unwind

8. 3 DNA Replication Unzip

8. 3 DNA Replication DNA unwinding and unzipping process

8. 3 DNA Replication Proteins carry out the process of replication. • Free-floating nucleotides form hydrogen bonds with the template strand. nucleotide The DNA molecule unzips in both directions.

8. 3 DNA Replication – DNA polymerase enzymes bond the nucleotides together to form the double helix. – Polymerase enzymes (ligase) form covalent bonds between nucleotides in the new strand nucleotide DNA polymerase

8. 3 DNA Replication Leading and lagging strands • Leading strand: it is going to replicate continously • Lagging strand: it is going to replicate by patches. DNA structure and Replication: Crash Course Biology #10 https: //www. youtube. com/watch? v=8 k. K 2 zwj. RV 0 M

8. 3 DNA Replication • Two new molecules of DNA are formed, each with an original strand a newly formed strand. • DNA replication is semiconservative. original strand Two molecules of DNA new strand

8. 3 DNA Replication is fast and accurate. • DNA replication starts at many points in eukaryotic chromosomes. There are many origins of replication in eukaryotic chromosomes. • DNA polymerases can find and correct errors.

8. 3 DNA Replication Practices (Optional) For the sake of knowledge. • Create a concept map with the following words, remember to use linking words. DNA polymerase, helicase, ligase, nucleotides, correct errors, bond nucleotides, purines, pyrimidines, template strand, new strand, semiconservative, A, G, T, C, Watson and Crick, Rosalind Franklin, double helix, hydrogen bonds, covalent bonds, replication, Chargaff rules, replication bubble. • Answer the following question: Mention 3 consequences of an incorrect DNA replication. • Discuss with a partner the formative assessment questions of page 224. • Quiz yourself on Kahoot. Search for a kahoot quiz and take it.

8. 3 DNA Replication CRISPR/Cas 9 • What is your opinion on being able to edit human DNA? • Are there any moral implications? • What are the benefits and consequences to using CRISPR-Cas 9? • How does editing our DNA relate to Darwin's theory of evolution, or from a creationist's perspective, intelligent design? • If we could edit out mutations, what would the world look like with a seemingly perfect human race?

8. 3 DNA Replication • What are the benefits and consequences to using CRISPR? • How does editing our DNA relate to Darwin's theory of evolution, or from a creationist's perspective, intelligent design? • If we could edit out mutations, what would the world look like with a seemingly perfect human race?

8. 3 DNA Replication