5 3 Regulation of the Cell Cycle Internal

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5. 3 Regulation of the Cell Cycle Internal and external factors regulate cell division.

5. 3 Regulation of the Cell Cycle Internal and external factors regulate cell division. • External factors include physical and chemical signals. • Growth factors are proteins that stimulate cell division. – Most mammal cells form a single layer in a culture dish and stop dividing once they touch other cells.

13. 1 Ecologists Study Relationships Bell. WORK!!!! Do it now. What is it called

13. 1 Ecologists Study Relationships Bell. WORK!!!! Do it now. What is it called when some cells in your body won’t stop dividing (mitosis). Hint: it kills 12% of humans worldwide.

5. 3 Regulation of the Cell Cycle CANCER • when cells divide and grow

5. 3 Regulation of the Cell Cycle CANCER • when cells divide and grow uncontrollably, forming tumors and invading the body.

5. 3 Regulation of the Cell Cycle • Apoptosis is when cells die automatically/normally

5. 3 Regulation of the Cell Cycle • Apoptosis is when cells die automatically/normally

5. 3 Regulation of the Cell Cycle Cell division is uncontrolled in cancer. •

5. 3 Regulation of the Cell Cycle Cell division is uncontrolled in cancer. • When cancer cells enter the blood, it spreads through the body (metastacizes). This is VERY bad. normal cell cancer cell bloodstream

5. 3 Regulation of the Cell Cycle Symptoms • Vary widely • “The Great

5. 3 Regulation of the Cell Cycle Symptoms • Vary widely • “The Great Imitator”

5. 3 Regulation of the Cell Cycle Tumors are lumps of cancer cells •

5. 3 Regulation of the Cell Cycle Tumors are lumps of cancer cells • Two Types 1. Benign tumors remain clustered and can be removed. 2. Malignant tumors metastasize (spread)

5. 3 Regulation of the Cell Cycle • About half of people who get

5. 3 Regulation of the Cell Cycle • About half of people who get treatment for malignant cancer die from it

5. 3 Regulation of the Cell Cycle • What causes cancer? • causes of

5. 3 Regulation of the Cell Cycle • What causes cancer? • causes of cancer are diverse, complex, and only partially understood. • Things known to increase risk (carcinogens): • Tobacco use • Radiation • Laziness • Obesity • Pollution • The Sun

5. 3 Regulation of the Cell Cycle How to avoid cancer: • • •

5. 3 Regulation of the Cell Cycle How to avoid cancer: • • • Don’t smoke cigarettes Don’t drink alcohol Exercise 3 -5 times per week Eat vegetables, fruit, and fish Avoid red meat (cows)

5. 3 Regulation of the Cell Cycle Curing Cancer • Cancer is a class

5. 3 Regulation of the Cell Cycle Curing Cancer • Cancer is a class of diseases – There will probably never be one “cure” • We still do not know: – What, exactly, causes cells to become cancerous? – How, exactly, do cancer cells work? • Focus on prevention. • So, be a doctor, and help figure it out!