323 Radiobiology Clinical Radiation Oncology Applied Radiation Biology
323 Radiobiology, Clinical Radiation Oncology Applied Radiation Biology and Radiotherapy Coordinated Research Projects of the International Atomic Energy Agency (IAEA) Oleg Belyakov, Elena Fidarova, Kirsten Hopkins, Rajiv Prasad, Eduardo Zubizarreta International Atomic Energy Agency
Introduction IAEA publication on was used as the manual for the CRP trial The Applied Radiation Biology and Radiotherapy (ARBR) Section of the Division of Human Health at the Department of Nuclear Sciences and Applications of IAEA performs a number of Coordinated Research Projects (CRPs).
Radiation Oncology CRPs • Randomized Phase III Clinical Trial of Stereotactic Body Radiation Therapy Versus Transarterial Chemoembolization in HCC - Hepatocellular Carcinoma (2014 -2018), which was designed to demonstrate equivalence/superiority of SBRT given upfront over TACE in terms of any disease progression in previously untreated patients with HCC; • Evidence-Based Assessment of Radiotherapy Demand Quality of Radiotherapy Services (2014 -2017), this project estimates the optimal and actual radiotherapy utilization (RTU) rates in developing countries using an evidence-based methodology; • Radiation Therapy Planning of Non-Small Cell Lung Cancer based on PET/CT (2014 -2018) was set to improve the clinical outcomes of patients with NSCLC in Member States (MS) by the use of PET/CT in radiation therapy planning.
Radiation Biology CRPs 3 D heart tissue scaffold (Prof Ratner) Mat. Tek Artificial human skin (Prof Belyakov) • Strengthening of Biological dosimetry in IAEA Member States: Improvement of current techniques and intensification of collaboration and networking among the different institutes (2012 -2016); • Safety and Optimisation of Radiation Sterilisation in Tissue Banking: Studies on Functional Properties of Irradiated Tissue Grafts (2010 -2015); • Instructive Surfaces and Scaffolds for Tissue Engineering Using Radiation Technology (2014 -2018).
Conclusions: 2 recent Special Issues published Special issue of Clinical Oncology journal, see editorial: Barton, M. B. , E. Zubizarreta, and M. Gospodarowicz, Radiotherapy in Low- and Middle-income Countries. What Can We Do Differently? Clin Oncol (R Coll Radiol), 2017. 29(2): p. 69 -71 Special issue of Genome Integrity journal, see editorial: Hande P, Sharan R, Belyakov O. Strengthening biological dosimetry in member states of the international atomic energy agency. Genome Integr 2016; 7: 1
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