2010 Guidelines 2010 Clinical Practice Guidelines for the

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2010 Guidelines 2010 Clinical Practice Guidelines for the Diagnosis and Management of Osteoporosis in

2010 Guidelines 2010 Clinical Practice Guidelines for the Diagnosis and Management of Osteoporosis in Canada Papaioannou A, et al. CMAJ 2010 Oct 12. [Epub ahead of print].

2010 Guidelines Introduction and Key Changes to the Guidelines Section One

2010 Guidelines Introduction and Key Changes to the Guidelines Section One

2010 Guidelines Development of the Guidelines • Key stakeholders were surveyed to identify priorities

2010 Guidelines Development of the Guidelines • Key stakeholders were surveyed to identify priorities • Systematic literature reviews were conducted in two key areas – – Fracture risk assessment Therapies for osteoporosis • Graded recommendations were developed based on these reviews Papaioannou A, et al. CMAJ 2010 Oct 12. [Epub ahead of print].

2010 Guidelines Target Population • Women and men > 50 years of age •

2010 Guidelines Target Population • Women and men > 50 years of age • Other fracture-risk groups are beyond the scope of these guidelines Papaioannou A, et al. CMAJ 2010 Oct 12. [Epub ahead of print].

2010 Guidelines Key Changes from 20021 to 20102: Fracture Risk Assessment • 10 -year

2010 Guidelines Key Changes from 20021 to 20102: Fracture Risk Assessment • 10 -year fracture risk prediction tools incorporate clinical risk factors beyond BMD for improved clinical decision making: – CAROC: Joint initiative of the Canadian Association of Radiologists and Osteoporosis Canada 3 OR – FRAX: Fracture Risk Assessment Tool developed by the World Health Organization 4 1. Brown JP, Josse RG. CMAJ 2002; 167(10 Suppl): S 1 -34. 2. Papaioannou A, et al. CMAJ 2010 Oct 12. [Epub ahead of print]. . 3. Leslie WD, Berger C, Langsetmo L, et al. Osteoporos Int. In press. 4. Leslie WD, Lix LM, Langsetmo L, et al. Osteoporos Int. In press.

2010 Guidelines Key Changes from 20021 to 20102 • Increased focus on the clinical

2010 Guidelines Key Changes from 20021 to 20102 • Increased focus on the clinical impact of fragility fractures • Increased focus on the care gap that exists in the identification and treatment of high-risk individuals 1. Brown JP, Josse RG. CMAJ 2002; 167(10 Suppl): S 1 -34. 2. Papaioannou A, et al. CMAJ 2010 Oct 12. [Epub ahead of print].

2010 Guidelines Key Changes from 20021 to 20102 (cont’d) • Higher daily vitamin D

2010 Guidelines Key Changes from 20021 to 20102 (cont’d) • Higher daily vitamin D supplementation (D 3)3 – 400 – 1000 IU for individuals < 50 years – 800 – 2000 IU for individuals > 50 years • Lower daily calcium intake (from all sources): 1200 mg • Updated evidence-based approach to therapies 1. Brown JP, Josse RG. CMAJ 2002; 167(10 Suppl): S 1 -34. 2. Papaioannou A, et al. CMAJ 2010 Oct 12. [Epub ahead of print]. 3. Hanley DA, et al. CMAJ 2010; 182: E 610 -E 618.

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2010 Guidelines 2010 Clinical Practice Guidelines for the2010 Guidelines 2010 Clinical Practice Guidelines for the
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