18 FFDG National Oncologic PET Registry NOPR 18
- Slides: 31
18 F-FDG
National Oncologic PET Registry (NOPR)
18 F-FDG PET/CT μόλυνση αγγειακού μοσχεύματος Sah BR et al. Eur J Vasc Endovasc Surg 2015; 49: 455 -64
Ο ρόλος της 18 F-FDG PET/CT στην ανάδειξη μόλυνσης αγγειακού μοσχεύματος 25ασθενείς Ευαισθησία 93% Ειδικότητα 70% PPV 82% NPV 88% FDG PET analysis (four point scale) Grade Ι: uptake ≤ background (-) Grade II: uptake ≤ soft tissue (-) Grade III: moderate uptake ≥ soft tissue (+) Grade IV: strong uptake comparable with bladder (+) Brukking et al. Eur J Vasc Endovasc Surg 2010; 40, : 348 -354
Ο ρόλος της 18 F-FDG PET/CT στην ανάδειξη μόλυνσης αγγειακού μοσχεύματος FDG PET analysis (five point scale) Grade 1: uptake ≤ background (-) Grade 2: mildly increased but diffuse FDG uptake along the graft Grade 3: focal but only mild FDG uptake or strong diffuse FDG uptake along the graft (+) Grade 4: focal and intense FDG uptake (+) Grade 5: focal and intense FDG uptake (+) plus CT findings Mild uptake: less than twice the blood pool activity in the ascending aorta Intense uptake: more than twice the blood pool activity in the ascending aorta 27ασθενείς με PVGi. S Ευαισθησία 100% Ειδικότητα 86% PPV 96% NPV 100% Διαγνωστική ακρίβεια: 97% Sah BR et al. Eur J Vasc Endovasc Surg 2015; 49: 455 -64
3 years after femoro-femoral Gore-Tex graft SUVmax=1, 1 16 years after aorto-bifemoral Dacron graft SUVmax=2, 5 Keidar et al. J Nucl Med 2014; 55: 392 -5
Bruggink et al. Semin Vasc Surg 2011; 24: 182 -90
Πρόσληψη ανάλογα με τον παθογόνο μικροοργανισμό q No studies are available for graft infection q Staphylococcus epidermidis (↓↓ 18 F-FDG) V Staphilococus aureus (low virulence of the pathogen and limited leukocyte infiltration ) Lankinen P et al. EJNMMI Research 2012; 2(1): 1 -10
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