1 Frequency and course of glomerular lesions associated

表 1 Frequency and course of glomerular lesions associated with Preeclampsia Lesion Endotheliosis Foam cells Subendothelial deposits GBM reduplication Fibrin or related products Focal segmental glomerulosclerosis Frequency Invariable Rare peripartum, more frequent postpartum Frequent peripartum More common in severe disease Rare by light microscopy; frequent by EM and IF Variable 35%(7/20, ref. 108) 45%(19/42, ref. 146) 71%(13/19, ref. 145) Course Reversible over weeks to months Resolve EM deposits resolve over first week, Ig staining resolve over 2 -3 months Usually resolve rapidly, may persist for months Resolve over weeks Not clinically progressive Heptinstall’s Pathlogy of the Kidney Sixth Edition p 784, Lippincott Williams & Wilkins, Philaderphia. 2007.

図 3 GBM reduplication 係蹄的の二重化

図 4 Fibrin or related products IF, Fibrinogen

図 5 Focal segmental glomerulosclerosis