1 7 AMINES AND AMIDES AMINES Amines are
- Slides: 21
1. 7 AMINES AND AMIDES
AMINES Amines are derivatives of ammonia molecules that contain a nitrogen atom bonded to one or more alkyl groups on each molecule. Many amines have strong, unpleasant odours. ex. putrescine cadaverine
COMMON AMINES
NAMING PRIMARY AMINES Take the “e” off the end of the alkane name and add the suffix “amine. ” ex. CH 3 NH 2 is methanamine An aromatic compound with NH 2 attached to a benzene ring is aniline.
NAMING SECONDARY AND TERTIARY AMINES ●begin with an amine name based on the longest alkyl group ●use the locator, N, to indicate the attachment of additional chains to the N atom ex. N-ethyl-N-propylbutan-1 -amine
EXAMPLE 1: NAME EACH OF THE FOLLOWING AMINES. a) b)
naming cont’d c) d)
EXAMPLE 2: Draw each of the following amines with ethyl as the attached alkyl groups. Then name each structure. a) a primary amine
EXAMPLE 2 cont’d b) a secondary amine c) a tertiary amine
PROPERTIES OF AMINES ●small amines are soluble in water ●N-C and N-H bonds are polar ●causes more VDW forces and more energy needed to break bonds ●higher MP and BP than their corresponding hydrocarbon compounds ●primary amines have higher BP’s than secondary bc they can form 2 H bonds. ●secondary amines can form 1 H bond and tertiary cannot form any
AMIDES Amides are structurally similar to esters except the two chains are joined by a nitrogen atom next to a carbonyl group instead of an oxygen atom.
NAMING AMIDES three parts: ●the first part from the amine ●the second part from the acid ●the ending -amide
EXAMPLE 3: NAME EACH OF THE FOLLOWING AMIDES. a) b)
EXAMPLE 4: Draw the structure of Nethylpropanamide
PROPERTIES OF AMIDES ●small amides are soluble b/c the N-H groups form H bonds with water ●the longer the carbon chain, the less soluble the amide
PREPARATION OF AMINES 1. alkyl halide + ammonia ---> primary amine ex. iodoethane + ammonia ---> ethanamine
PREPARATION OF AMINES 2. alkyl halide + 1 amine ---> 2 amine ex. iodoethane + ethanamine ---> N-ethylethanamine
PREPARATION OF AMINES 3. alkyl halide + 2 amine ---> 3 amine ex. iodoethane + N-ethylethanamine ---> N, Ndiethylethanamine
SYNTHESIS OF AMIDES - involves a condensation reaction of a carboxylic acid and ammonia OR a primary or secondary amine.
HOMEWORK: p. 58 #1, 2 p. 60 #1, 2 p. 62 #1 - 5
- Insidan region jh
- Amines chemsheets
- Basicity of amines
- Guanidine basicity
- Ester nomenclature
- Carboxylate ion
- Amides reactions
- Name amides
- Amide hydrolysis
- Naming amides
- Vital amines vitamins
- Amino acid optical isomers
- Amine group
- Base forte
- Amine vasoactive
- Physical properties of amines
- Chapter 20
- Amines hydrogen bonding
- Carboxylic acid and amine reaction
- Dissociation des acides aminés
- Primary amine
- O ch